Stephen G. Kayes, Ph.D.

Stephen G. Kayes, Ph.D.
Professor
Phone: (251) 460-6768
Fax: (251) 460-6771
skayes@usouthal.edu

RESEARCH INTEREST

Main research is in area of host immunologic responses to parasitic infection as they relate to the pathogenesis of disease. Special emphasis on mechanisms relating to the regulation of pulmonary granuloma formation in toxocariasis and the development of a synchronous, artificial model for in vitro studies. Also interested in the regulation of eosinophil function and characterization of host pathologies as a result of sustained high eosinophilias. Currently, working on genetic vaccines (naked DNA) for helminthic diseases. Most recent studies have focused on role of perinatal infection of humans with Toxocara canis and its possible relationship to the development of asthma, especially in minority populations.

EDUCATION

University of Wisconsin-Madison	B.S.	1971	Zoology

Tulane University-New Orleans	M.S.	1973	Parasitology

University of Iowa-Iowa City	Ph.D	1977	Anatomy

PROFESSIONAL EXPERIENCE

1994-	Visiting Professor, Department of Pediatrics, Div. of Biochemical Genetics,
	University of Wisconsin--Madison (Sabbatical with Dr. Jon A. Wolff)
1991-	Professor, Department of Microbiology and Immunology,
	University of South Alabama, Mobile, AL 36688
1990-	Professor, Department of Structural and Cellular Biology,
	University of South Alabama, Mobile, AL 36688.
1987-	Associate Professor, Department of Microbiology/Immunology,
	University of South Alabama, Mobile, Alabama 36688
1986-1991	Associate Professor, Department of Anatomy and Cell Biology,
	University of South Alabama, Mobile, Alabama 36688
1981-1986	Assistant Professor, Department of Anatomy; Joint Secondary appointment,
	Assistant Professor, Department of Microbiology and Immunology, University of South
	Alabama, Mobile, Alabama 36688
1977-1981	Research Associate, Department of Microbiology, Vanderbilt University and Veterans
	Administration Medical Center, Nashville, Tennessee (With Dr. Daniel G. Colley)
1976-1977	NIH Predoctoral Fellow in Anatomy
1975-1976	Laboratory Teaching Assistant Physical Therapy Neuroanatomy; Laboratory Teaching
	Assistant Medical Neuroanatomy; Special Tutor for Economic Opportunity Program
	tudents in Neuroanatomy, University of Iowa, Iowa City, Iowa
1974-1975	Laboratory Teaching Assistant Physical Therapy Gross Anatomy,
	University of Iowa, Iowa City, Iowa
1973-1974	Laboratory Teaching Assistant Medical Histology,
	University of Iowa, Iowa City, Iowa
1973	Director of Medical Parasitology Laboratory, Tulane
	University Medical School, New Orleans, Louisiana
1972-1973	NIH Predoctoral Fellow in Parasitology
1972	Laboratory Assistant in Medical Parasitology, Tulane
	University Medical School, New Orleans

TEACHING RESPONSIBILITIES

Cell Biology and Neuroscience

110	Contact hours in Medical Neuroanatomy	(1981-1988)
120	Contact hours in Medical Histology	(1988-)
	Course Director, Medical Histology	(1990-1993)
	Course Director, Medical Histology	(2001-2003)
5 hrs	Graduate Cell Biology--Chemotaxis and Motility	(1989-1990)
2 hrs	Graduate Cell Biology--Membrane Structure	(2001-)
10 hr	Medical Terminology Course (BEAR Summer Program)	(1992-1994)
12 hr	Histology Portion BEAR Anatomy Introduction Course	(2002-)
Microbiology & Immunology:
	Entire block of Medical Parasitology	(1981-)

EXTRAMURAL RESEARCH SUPPORT

NIH, R01 AI 19968; "Nematode-induced Pulmonary Granuloma Formation," Stephen G. Kayes, Principal Investigator; $50,556, First Year; $168,447 Total Award; 4/1/83-11/30/86; Funded.

NIH, R01 AI 19968-04; Competitive Renewal; Stephen G. Kayes, Principal Investigator; $108,740 First Year; $522,923 Total Award; 7/1/87-6/30/92; Funded.

American Heart Association, Alabama Affiliate; 870034; "Immunopathology of Eosinophilic Myocarditis," Stephen G. Kayes, Principal Investigator; $20,000, First Year; $40,000 Total Award. 7/1/87-6/30/89; Funded.

NIH, BRS Shared Instrumentation Grant; S10 RR 04125-01; Flow Cytometry Resource Upgrade. Raymond B. Hester, Ph.D. Principal Investigator, S. G. KAYES.Subproject: Immunopathologic mechanisms in parasitic infections. $214,064 Total Award. 4/11/88-4/10/89; Funded.

American Heart Association, Alabama Affiliate; 870034 "Immunopathology of Eosinophilic myocarditis," Stephen G. Kayes, Principal Investigator; $23,985, Third Year Competitive Renewal. 7/1/89-6/30/90. Funded.

NIH, DRR/BRS Shared Instrumentation Grant; S10 RR 06520-01; ACAS 570 Anchored Cell Analyzer and Sorter. Raymond B. Hester, Ph.D. Principal Investigator, S. G. KAYES. Subproject 6: Regulation of Eosinophil Degranulation. $290,495 Total Award. 12/01/90-11/30/91; Funded.

American Heart Association, Alabama Affiliate; Al-G-950021; "Naked DNA Vaccine-Induced Immune Responses in Schistosomiasis. Principal Investigator, S. G. Kayes. $30,000, First Year, $60,000, Total Award. 7/1/95-6/30/97. Funded.

HONORS AND AWARDS

Outstanding Faculty Recognition at Honors Convocation of the College of Medicine, Chosen by Graduating Seniors, Class of 1995, 1997, 1999, 2000, and 2001.

HONORS AND AWARDS WON BY MY STUDENTS

Richard E. Jones (1988)	Outstanding Paper Presented at International Association
	for Aquatic Animal Medicine, Orlando, FL.
F. J. Herndon (1991)	Outstanding Student Paper presented at Annual Meeting of American
	Society of Parasitologists, Madison, WI.
F. J. Herndon (1992)	Byrd-Dunn Award, Best Scientific Presentation,
	Southeastern Society of Parasitologists, Mobile, AL.
J. S. Jackson (1995)	Byrd-Dunn Award, Best Scientific Presentation,
	Southeastern Society of Parasitologists, Knoxville, TN.

PROFESSIONAL SOCIETY MEMBERSHIPS

American Association of Anatomists (1982)

American Society of Parasitologists (1971-)

Member, Endowed Lecture Committee	(1985-89)
Chair, Endowed Lecture Committee	(1986)
Member, Education Committee	(1989)
Chair, Bylaws Revision Committee	(1993-)
Chair, Mentor Award Committee	(1995-98)
Member, Council	(1991)
Member, Business Advisory Committee	(2001-)
Chair, Business Advisory Committee	(2002-)
Member, In Memoriam Committee	(2001-)
Chair, Local Organizing Committee for	(2002-)
Annual Mtg — 2005

American Society of Tropical Medicine and Hygiene (1971-)

American Society for the Advancement of Science (1971-)

Society of Sigma Xi (1982-, elected)

Southeastern Society of Parasitologists (1982-)

Chair, Bylaws Revision Committee	(1987-88)
President Elect	(1989-90)
President	(1990-91)
Immediate Past President	(1991-92)
Chair, Local Organizing Commitee	(1991-92)

Helminthological Society of Washington (1987-, elected)

American Association of Immunologists (1990-, elected)

EDITORIAL BOARDS/JOURNAL CONSULTANTSHIPS

Editorial Board, Journal of Parasitology (1993-95)

Associate Editor for Helminth Immunology; Journal of Parasitology (1995 -)

EXTRAMURAL SERVICE

Reviewer, Journal of Parasitology

Reviewer, American Journal of Tropical Medicine Hygiene

Reviewer, Archives of Ophthalmology

Reviewer, Experimental Parasitology

Reviewer, Parasite Immunology

Reviewer, Veterinary Parasitology

Reviewer, Immunology Research

Reviewer, ACTA Parasitogica

Reviewer, American Journal of Pathology

Member of NIH Ad Hoc Study Section (Tropical Medicine and Parasitology)

Member of NSF Ad Hoc Study Section (Cellular Physiology)

UNIVERSITY SERVICE

Vanderbilt University:

President's Task Force: Opportunities For the Handicapped. (1977-1981)

University of South Alabama:

Faculty Senator from College of Medicine (1981-4, 1999-02)
Member of Senate Committee on Promotions, Salary and Tenure (1981-4, 1999-02)
Chair of Senate Committee on Promotions, Salary and Tenure (1984)
Member of Executive Committee of Faculty Senate (1984)
Caucus Leader, College of Medicine (2001-2)
Member Search Committee: Dean of Arts and Sciences (1983)
Member Search Committee: Vice President For Academic Affairs (1983-4)
Member Search Committee: College of Allied Health (2 Faculty) (1987)
Member Search Committee: Department of Structural & Cellular Biology (1989)

College of Medicine:

Member of Animal Care and Use Committee (1981-3)

Faculty Assembly Member At Large (1984-7)

Member of Executive Committee (1984-7)

Member of Student Evaluation and Promotion Committee (1985-8)

Chair of Basic Sciences Subcommittee of SEPC (1987-8)

Member of Student-Faculty Liaison Committee (1985-6)

Member of Research Advisory Committee (1986-8)

Member of Biomedical Enrichment and Recruitment Committee (1987-90)

Member of LCME Clinical Sciences Subcommittee (1987-8)

Member of Flow Cytometry Advisory Committee (1987- )

Member of Cell and Molecular Biology Committee (1987-)

Member of Biomedical Library Directorship Search Committee (1990)

Member of Committee on Standards in the Conduct of Research (1990-3)

Member of Faculty Committee on Appointments, Promotions, & Evalualtion (1992-5)

Member of LCME Basic Sciences Subcommittee (1995)

Graduate Program in Basic Medical Sciences:

Member of Student Promotion and Evaluation Committee (1983-6)

Chair, First Year Graduate Curriculum Revision Committee (2001-)

Department of Structural and Cellular Biology:

Member of Graduate Affairs Committee (1992- )

Thesis Committees:

Barbara Christie-Pope, Department of Pharmacology

Krista Gaines, Department of Anatomy

Susan Ledoux, Department of Anatomy

Michael Amos, Department of Microbiology

Mathew von Wronski, Department of Biochemistry

Richard E. Jones, Department of Anatomy, (Director) Awarded 8/19/91

Michelle E. Perry, Department of Physiology

Robert Speed, Department of Microbiology

Pippa Abston, Department of Microbiology

Filomena Dimayuga, Department of Microbiology

Fred J. Herndon, Department of Microbiology, (Director) Awarded 6/19/92

Herman Staats, Department of Microbiology

Terry Tumpe, Department of Microbiology

Les DePuy, Department of Biochemistry

Julia S. Jackson, Department of Biological Sciences, (Director, MS Thesis)

Emily Burke, Department of Biochemistry

Sean Dobson, Department of Biochemistry

Summer Research Students:

Sarah Zachos, Yale University (1983)

Donnie Scott, University of South Alabama (1984)

Valerie Marshall, Xavier University (1985, 86)

Fred J. Herndon, University of South Alabama (1986)

Amy Rapp, University of Southern Mississippi (1988)

Sarah Eastman, University of South Alabama(1999)

Jennifer Griffin, Mobile University (1999, 2000)

Chavaro Floyd, University of South Alabama(2001)

Senior Medical Student Research Elective:

Donna Murphy (1987)

Visiting Lecturer/Invited Seminars

Walter Reed Army Institute of Research: Summer Course in Tropical Medicine, (1982)

University of Wisconsin School of Veterinary Medicine: Invited Seminar, (1982)

The 13th Annual Fancy Gap Immunoparasitology Workshop: Invited Seminar, (1986)

Ann. Mtg of Southeastern Society of Parasitologists: Invited Symposium Participant,

Seventh Annual HLA Educational Seminar: Invited Symposium Participant, (1988)

Center For Research and Training in Parasitic Diseases: Invited Seminar (1989)

Upjohn Pharmaceutical Company; Kalamazoo, MI: Invited Seminar (1990)

Purdue University Veterninary School of Medicine; West Lafayette, IN: Invited Seminar (1990)

Mobile County Health Department. Toxocara canis and asthma. Time for another study. (1999)

American Chemical Society — Mobile Chapter; What’s eating you? (2001)

International Baccalaureate Program, Murphy High School, Mobile, AL. Introduction to Immunology. (2001)

University of West Florida, Pensacola, FL. Parasites and Sickle Cell Disease. Not just for malaria anymore. (2001)

American Society of Parasitologists, Albuquerque, NM. Sickle cell disease and asthma. Who let the dogs’ worms out? (2001)

University of South Alabama, College of Allied Health. Series of Lectures on Cestodes and Trematodes (2002)

University of South Alabama, Society of Sigma Psi Lecturer. Talk entitled, “What’s Eating You?” (2002)

University of South Alabama, Di Vinchi Club Lecturer. Talk entitled, “What’s Eating You?” (2002)

PUBLICATIONS

KAYES, S. G., Eastman, S., Griffin, J., Floyd, C., McKinnley, J., and W., Wilson-Little, F.2002. Immuno-inflammatory cytokines in patients with sickle cell disease and who are seropositive for the canine roundworm, Toxocara canis. (In prep).

KAYES, S. G., Eastman, S., Sindel, L. W., Wilson-Little, F. 2002. Seroprevalence of Toxocara canis in asthmatics and patients with sickle cell disease. (In prep).

KAYES, S. G., Cusick, S., Griffin, J., McKinley, J., Floyd, C., Mulekar, M., and Wilson, F.2002. Helminths and asthma redux: A role for Toxocara canis. Proceedings of 10^th International Congress of Parasitology — ICOPA X: Symposia, Workshops, and Contributed Papers: 562-565.

KAYES, S. G. 1997. Human toxocariasis and the visceral larva migrans syndrome: Correlative immunopathology. In: Immunopathogenetic Aspects of Disease Induced by Helminth Parasites. D. O. Freedman, Ed.; Karger, Basel. Chem. Immunol. 66:99-124.

S. G. KAYES, R. C. Shaneyfelt, C. Monteiro, and J. J. O’Brien. 1997. Overproduction of Sm28GST in a baculovirus expression vector and its use to evaluate the in vivo immune responses of mice vaccinated against Schistosoma mansoni with naked DNA encoding the Sm28GST gene. J. Parasitol. 84:764-770.

KAYES, S. G., and J. A. Wolff. 1996. Gene transfer techniques in genetic vaccination. In: Encylcopedia of Molecular Biology and Molecular Medicine. R. A. Meyers, Ed.; VCH Publishers, Inc. Weinheim. Vol. 2: 430-439.

Yoshikawa, S., S. G. KAYES, S. L. Martin, and J. C. Parker. 1996. Eosinophilia-induced vascular and airway remodeling and hyperresponsiveness in rat lungs. J. Appl. Physiol. 81:1279-1287. (Color plate selected for Journal Cover)

Ferens, W. A., and S. G. KAYES. 1994. Mice infected with Toxocara canis are resistant to challenge with the non-related helminth, Trichinella spiralis. Acta Parasitol. 39:37-40.

Jones, R. E, F. D. Finkelman, R. B. Hester and S. G. KAYES. 1994. Toxocara canis: Failure to find IgE receptors (FcεR) on eosinophils from infected mice suggests that murine eosinophils do not kill helminth larvae by an IgE-dependent mechanism. Exp. Parasit. 78:64-75.

Yoshikawa, S., S.G. KAYES, and J.C. Parker. 1993. Eosinophils increase lung microvascular permeability via the peroxidase-hydrogen peroxide-halide system: Bronchoconsrtriction and vasoconstriction are unaffected by eosinophil peroxidase inhibition. Am. Rev. Resp. Dis. 147:914-920.

Herndon, F.J., and S.G. KAYES. 1992. Depletion of eosinophils by anti-IL-5 mAb treatment of mice infected with Trichinella spiralis does not alter parasite burden or immunologic resistance to reinfection. J. Immunol. 149:3642-3647.

Fujimoto, K., S. Yoshikawa, S. Martin, S. G. KAYES, and J. C. Parker. 1992. O₂ Radical scavengers protect against eosinophil-induced injury in isolated perfused rat lungs. J. Appl. Physiol. 73:687-694.

Schaffer, S. W., E. R. Dimayuga and S. G. KAYES. 1992. Development and characterization of a model of eosinophil-mediated cardiomyopathy in rats infected with Toxocara canis. Am. J. Physiol. 31:H1428-H1434.

Deardorff, T. L., R. E. Jones, and S. G. KAYES. 1991. Adherence of eosinophils to the epicuticle of infective juveniles of Anisakis simplex (Nematoda: Anisakidae). Proc. Helminthol. Soc. Wash. 58:131-137.

Dimayuga, E.,M. B. Stober and S. G. KAYES. 1991. Eosinophil peroxidase levels in hearts and lungs of mice infected with Toxocara canis . J. Parasitol. 77:461-466.

Cookston, M., M. Stober, and S. G. KAYES. 1990. Eosinophilic myocarditis in CBA/J mice infected with Toxocara canis. Am. J. Pathol.136: 1137-1145.

Fujimoto, K., J. C. Parker and S. G. KAYES. 1990. Activated eosinophils increase vascular permeability and resistance in isolated perfused rat lungs. Am. Rev. Respir. Dis. 142:1414-1421.1

Jones, R. E., T. L. Deardorff and S. G. KAYES. 1990. Anisakis simplex: Histopathological changes in experimentally infected CBA/J mice. Exp. Parasit. 70:305-313.

Perry, M. L., S. G. KAYES, J. W. Barnard and A. E. Taylor. 1990. Effects of phorbol myristate acetate‑stimulated human neutrophils and monocytes on rat lung. J. Appl. Physiol. 68:235-240.

KAYES, S. G., R. E. Jones, and P. E. Omholt. 1988. Pulmonary granuloma formation in murine toxocariasis: Transfer of granulomatous hypersensitivity using bronchoalveolar lavage cells. J. Parasitol.

KAYES, S. G., R. E. Jones and P. E. Omholt. 1987. Use of bronchoalveolar lavage (BAL) to compare local pulmonary immunity with the systemic immune response of mice infected with Toxocara canis. Infect. Immun. 55:2132-2136.

KAYES, S. G. 1986. Nonspecific allergic granulomatosis in the lungs of mice infected with large but not small inocula of the canine ascarid, Toxocara canis. Clin. Immunol. Immunopathol. 41:55‑65.

KAYES, S. G., P. E. Omholt and R. B. Grieve. 1985. Immune responses of CBA/J mice to graded infections with Toxocara canis. Infect. Immun. 48:697-703.

KAYES, S. G. 1984. Spleen cell responses in experimental murine toxocariasis. J. Parasitol. 70:522-529.

KAYES, S. G. and D. G. Colley. 1984. Immunoregulation in Experimental Schistosomiasis. II. Soluble egg antigen‑induced chronic spleen cell augmentation of baseline lymphocyte reactivity. Cell. Immunol. 83:152-160.

KAYES, S. G. and D. G. Colley. 1984. Immunoregulation in Experimental Schistosomiasis. III. Role of macrophages in soluble egg antigen-induced chronic spleen cell augmentation of baseline lymphocyte reactivity. Cell. Immunol. 83:161-169.

KAYES, S. G. and J. A. Oaks. 1980. Toxocara canis: Role of the T lymphocyte in murine visceral larva migrans and its relationship to the onset of eosinophilia. Exp. Parasitol. 49:47-55.

Oaks, J. A. and S. G. KAYES. 1979. Artificial hatching and culture of Toxocara canis second stage larvae. J. Parasitol. 65:969 970.

KAYES, S. G. and J. A. Oaks. 1978. Development of the granulomatous response in murine toxocariasis. Initial events. Am. J. Pathol. 93:277 294 .

KAYES, S. G. and J. A. Oaks. 1976. The effect of inoculum size and length of infection on the distribution of Toxocara canis in the mouse. Am. J. Trop. Med. Hyg. 25:573 581.

ABSTRACTS/NATIONAL PRESENTATIONS

KAYES, S. G., Cusick, S., Griffin, J., McKinley, J., Floyd, C., Mulekar, M., and Wilson, F. 2002. Helminths and asthma redux: A role for Toxocara canis. 10th International Congress of Parasitology — ICOPA X. S23-2-B:153a.

KAYES S. G., J. K. Griffin, S. Eastman, C. Floyd, J. McKinley, and F. Wilson. 2001. Inflammatory cytokines in sickle cell disease patients seropositive for Toxocara canis. American Society of Parasitologists 76:34a.

KAYES, S. G. 2001. Sickle cell disease and asthma. Who let the dogs’ worms out? American Society of Parasitologists 76:27a.

KAYES S. G., J. K. Griffin, S. Eastman, C. Floyd, J. McKinley, and F. Wilson. 2001. Inflammatory cytokines in sickle cell disease patients seropositive for Toxocara canis. Southeastern Society of Parasitologists 32:13a.

KAYES, S. G. and S. Eastman. 2000. Seroprevalence of Toxocara canis in asthmatics and non-asthmatics. Am. Soc. Parasitologists 75:143a.

Wilson-Little, F., L. Sindel, and S. G. KAYES. 2000. Is there a relationship between Toxocara canis infection, inflammation, and asthma in sickle cell disease? 24th Annual Meeting of Sickle Cell Disease Association of America 24:201a.

Eastman, S. and S. G. KAYES. 1999. Seroprevalence of Toxocara canis in asthmatic and non-asthmatic subjects. Southeastern Society of Parasitologists 31:10a.

KAYES, S. G. and J. C. Parker. 1999. Toxocara canis induces airway hyperresponsiveness and remodeling in acutely infected rats. American Society of Parasitologists 74:45a.

KAYES, S. G. and J. C. Parker. 1998. Can worms cause asthma? A breath of fresh air or just barking up the same old respiratory tree. Southeastern Society of Parasitologists. 30:28a.

Jackson, J.S., J. J. O'Brien, and S. G. KAYES. 1995. The effect of naked DNA vaccination on the granulomatous response to Schistosoma mansoni eggs in the livers of infected mice. Southeastern Society of Parasitologist. (Byrd-Dunn Award Winning Presentation).

KAYES, S. G., J. W. Tracy, and J. A. Wolff. 1995. Vaccination against Schistosoma mansoni using naked DNA: Creation of an eukaryotic expression vector encoding a parasite-specific glutathione S-transferase. Southeastern Society of Parasitologists.

KAYES, S. G., J. S. Jackson, J. J. O'Brien, J. Powell, J. W. Tracy, J. S. Lattendresse, and J. A. Wolff. 1995. Reduced egg accumulation in livers of Schistosoma mansoni-infected mice vaccinated with naked DNA. American Society of Parasitologists 70:184a.

KAYES, S. G., R. C., Shaneyfelt, C. Monteiro, and J. J. O’Brien. 1997. Production of antigen in a baculovirus expression vector system and its use to evaluate a polynucleeotide vaccine for schistosomiasis. American Society of Parasitologists 72:48a.

Yoshikawa, S., J. C. Parker, A. F. Siebert, and S. G. KAYES. 1992. The peroxidase-H2O2-halide system contributes to eosinophil-induced injury in isolated perfused rat lungs. FASEB

Parker, J. C., S. Yoshikawa, S. G. KAYES, A. G. Brady, and S. Martin. 1992. Sialodacryoadentitis virus increases eosinophil-induced damage in isolated rat lungs. FASEB.

Herndon, F. J. and S. G. KAYES. 1992. Mouse eosinophils do not mediate resistance or killing in secondary Trichinella spiralis infections. American Society of Parasitologists.

Herndon, F. J. and S. G. KAYES. 1991. Trichinella spiralis infection in mice depleted of eosinophils by mAb TRFK-5. American Society of Parasitologists. (Abstr). (Winner of Best Student Presentation Award)

Fujimoto, K., J. C. Parker, and S. G. KAYES. 1990. Effects of activated eosinophils on isolated perfused rat lungs. 1990 World Conference on Lung Health. (Abstr).

Cookston, M., M. Stober, and S. G. KAYES. 1990. Eosinophilic myocarditis in CBA/J mice infected with Toxocara canis. International Union of Pathologists, Mod. Pathol. 3:22A.

KAYES, S. G., J. C. Parker, K. Fujimoto and S. W. Schaffer. 1990. Eosinophil-mediated damage to isolated, perfused hearts or lungs. International Congress of Parasitology VII. (Abstr).

Dimayuga, E. and S. G. KAYES. 1989. Eosinophil peroxidase levels in hearts and lungs of mice infected with Toxocara canis. American Society of Parasitologists. (Abstr).

KAYES, S. G., M. B. Stober and R. B. Hester. 1988. Comparative analysis by flow cytometry of T cell subsets in lungs and spleens of mice infected with Toxocara canis. American Society of Tropical Medicine and Hygiene. (Abstr).

Jones, R. E., T. L. Deardorff and S. G. KAYES. 1988. Histopathology of experimental anisakiasis. American Society of Parasitologists (Abstr).

KAYES, S. G. and P. E. Omholt. 1987. Successful transfer of pulmonary granulomatous hypersensitivity in murine toxocariasis using bronchoalveolar lavage cells. American Society of Parasitologists (Abstr).

KAYES, S. G., P. E. Omholt and R. E. Jones. 1986. Use of bronchoalveolar lavage (BAL) to compare local pulmonary immunity with systemic immunity in mice infected with Toxocara canis. American Society of Tropical Medicine and Hygiene. (Abstr).

Jones, R. E., P. E. Omholt and S. G. KAYES. 1986. Comparison of immune responses to Toxocara canis in C57BL/6. SJL/J and B6D2F1 mice. American Society of Parasitologists. (Abstr).

KAYES, S. G. and P. E. Omholt. 1985. Characterization of the splenic lymphocyte spontaneously synthesizing DNA in mice infected with Toxocara canis. American Society of Parasitologists (Abstr).

KAYES, S. G. and P. E. Omholt. 1985. Eosinophils in experimental toxocariasis: Paradoxical effects of cyclophosphamide. American Society of Tropical Medicine and Hygiene. (Abstr).

KAYES, S. G. and P. E. Omholt. 1984. Granuloma formation around heterologous antigen coated particles is reduced in mice with experimental toxocariasis. Am. Soc. Trop. Med. Hyg. (Abstr).

Gaines, K. L., S. G. KAYES and G. L. Wilson. 1984. EMC virus infection in diabetes susceptible and resistant mice. Diabetes 33(S1):38a. (Abstr).

KAYES, S. G. 1984. Sensitivity of mice to graded infection with Toxocara canis American Society of Parasitologists. (Abstr).

KAYES, S. G. 1983. Toxocaral pneumonitis in CBA/J mice: A histopathologic study in glycol methacrylate. American Society of Parasitologists. (Abstr).

KAYES, S. G. 1983. Characterization of the splenic response in murine toxocariasis. American Society of Tropical Medicine and Hygiene. (Abstr).

Cox, B. A., L. W. Yielding and S. G. KAYES. 1983. Immune responses and protection from lethal challenge in mice infected with ethidium azide treated Trypanosoma brucei. American Society of Parasitologists. (Abstr).

Rand, T. H., S. G. KAYES and D. G. Colley. 1981. Eosinophils from mice with experimental toxocariasis: A method for obtaining and purifying peritoneal eosinophils, and a study of their responses to opsonized particles and to the lymphokine, eosinophil stimulation promoter (ESP). American Society of Tropical Medicine and Hygiene. (Abstr).

KAYES, S. G. and D. G. Colley. 1981. Mixed lymphocyte responses in acute and chronic murine schistosomiasis. American Society of Tropical Medicine and Hygiene. (Abstr).

KAYES, S. G., F. A. Lewis and D. G. Colley. 1980. Immunoregulation of in vitro lymphoproliferative responses of mice with chronic schistosomiasis mansoni. American Society of Tropical Medicine and Hygiene. (Abstr).

KAYES, S. G. and D. G. Colley. 1980. In vitro induction of suppressor cells and factors by exposure to Con A or schistosomal egg antigen (SEA) of spleen cells from normal or Schistosoma mansoni infected mice. Proceedings of IVth International Congress of Immunology (Paris) 12.3.15 (Abstr).

KAYES, S. G. and D. G. Colley. 1979. Inducement by concanavalin A or schistosome egg antigen of a soluble suppressive factor(s) from spleen cell cultures from mice chronically infected with Schistosoma mansoni. American Society of Tropical Medicine and Hygiene. (Abstr).

KAYES, S. G. and D. G. Colley. 1978. Induction of murine suppressor cell activity by schistosomal antigen preparations and concanavalin A. American Society of Parasitologists. (Abstr).

KAYES, S. G. and J. A. Oaks. 1977. The role of the T lymphocyte in the pathogenesis of murine toxocariasis. American Society of Tropical Medicine and Hygiene. (Abstr).

KAYES, S. G. and J. A. Oaks. 1974. Development of the persistent granuloma of visceral larva migrans in mice as a model for investigation of eosinophilic granulomata. American Society of Parasitologists. (Abstr).

KAYES, S. G. and J. A. Oaks. 1974. Cellular evolution of the persistent granuloma of visceral larva migrans in the murine host. 11th Annual Iowa State University Electron Microscopy Colloquium. (Abstr).

KAYES, S. G. and J. A. Oaks. 1973. Eosinophilia and the development of the chronic granuloma of visceral larva migrans. Southwestern Association of Parasitologists. (Abstr).

CHAPTERS

BOOKS

R. B. Chronister and S. G. KAYES 1981, 1982, 1984, 1985, 1986 and 1987. Medical Neuroanatomy. University of South Alabama. (Laboratory Manual, 68 pages).

KAYES, S. G. 1991, 1992. Medical Histology Laboratory Manual. University of South Alabama. (Laboratory Manual, 120 pages).

Medical Cell Biology. Goodman, S. R., Ed. 1994. J. B. Lippincott-Raven Publishers, Philadelphia. 288 pages.

Medical Cell Biology. Goodman, S. R.; Ed. 1998, 2nd Edition; J. B. Lippincott-Raven, Publishers, Phila. 320 pages. (Includes a Floppy disk of National Board-Styled Examination Questions edited by S.G. Kayes)

THESES/DISSERTATIONS

Characterization of the Cellular Evolution of the Persistent Granuloma of Visceral Larva Migrans in the Murine Host. M.S. Thesis. Tulane University, New Orleans. 113 pages, 1973.

An Investigation of the Role of the Thymus Derived Lymphocyte in the Pathogenesis of Murine Toxocariasis. Ph.D. Dissertation. University of Iowa, Iowa City. 116 pages, 1977.